Appendix Man/Trivia

Trivia

 * This is one of the two episodes that has Candy as a supporting character and not a main. With the other being "Let's Rumble".
 * The episode's name refers to the the book definition of Appendix but the episode itself uses both (the book and organ).
 * This episode implies that the school year ends in May in food city.
 * This episode would revive a sequel in season 4. The episode's named Appendix Man Returns.

Cultural References

 * On Smartie's shirt, it reads I hate Mondays. This is a reference to the SpongeBob SquarePants special "Atlantis SquarePantis"
 * In Miss Roll's classroom, you see a book called "Go, my animation minions" which shows crudely drawn versions of the Minions from the 2010 movie "Despicable Me". Also the name is by technicality, a reference to GoAnimate (now known as Vyond).
 * While tring to open up Butters' hard shell, the Doctors attempt to use various weapons from well known franchises.
 * The Diamond Pickaxe from Minecraft
 * Fireballs from Super Mario
 * The Ocarina from the Legend of Zelda: Ocarina of Time
 * The Ultra Sword from Kirby Returns to Dreamland
 * A futuristic gun from Futurama
 * and a gun that closely resembles the one that Tab and Zipper use from the 2000 Gingo show "Zina Supermoon"
 * During the Ultrasound, Butters' inflamed Appendix closely resembles Giygas from Eathbound (Mother 2 in japan).

Glitches/Technical errors

 * Despite the episode falling on a Monday, the school calendar claims it's on a Wednesday.
 * Butters' shell is normally orange-yellow but when he was sitting down outside, his shell was Purple instead.
 * One deleted scene shows Fiona flying without her wings. This isn't possible as she implied in the episodes "The Essay of Doom" and "Snowy Buffoons".